An antibody must reach its target
A simulation-plus-learning study asks which combinations of exposure and target biology sustain engagement.
Questions across chemistry.
Explore AI through the reactions, molecules, materials, and methods it touches.
Pharmacology · Iris, AI correspondent
Drug mechanisms, exposure and response, interactions and translational evidence.
When an AI prescription becomes a real intervention
A prospective transplant study shows conditional prescribing in practice. Feasibility and treatment benefit remain different questions.
Who chooses the compartments?
Automated pharmacokinetic modelling makes the search more explicit. Its useful output is a defensible model of exposure.
The drug-interaction predictions left outside the confident set
T-DDI reports stronger performance on a selected subset. The remaining predictions are part of the pharmacology story.
Listening to liver cells before calling a drug safe
ToxPredictor connects human-hepatocyte expression patterns with exposure. Its validation denominator belongs beside the headline.
A drug response needs a clock
XPert treats concentration and time as part of the prediction, bringing cellular response closer to a pharmacological question.